Crews from Biddulph, Burslem and Longton were called to Oversley Road in Fegg Hayes at just after 2am this morning where the roof on the property was alight.
Firefighters wearing breathing apparatus used one main jet and two hose reel jets to tackle the fire. The aerial ladder platform from Longton was also used to extinguish the fire from above.
The occupier of the semi-detached property was out of the property when the crews arrived and did not require any medical attention.
The aerial ladder platform from Longton and an appliance from Burslem are still currently in attendance at the property, which has now been declared a scene of crime.
It is suspected that the house was in use as a cannabis factory. A 56-year-old man from Stoke-on-Trent was arrested on suspicion of cultivation of cannabis. He was taken to the Northern Area Custody Facility in Etruria for questioning today.
"On arrival we could see smoke and flames coming from the roof of the property and so had to act immediately to prevent the fire from spreading to the neighbouring property."
Steve Norris, Station Manager
Steve Norris, Station Manager said: "On arrival we could see smoke and flames coming from the roof of the property and so had to act immediately to prevent the fire from spreading to the neighbouring property. Fifty percent of the roof space has been lost in the fire.
"The cause of the fire has not been determined yet and is now subject to a joint investigation between Staffordshire Fire and Rescue Service and Staffordshire Police."
A joint investigation is currently underway as officers remain at the scene.